fredag 12 februari 2016

FXR Gene

http://www.ncbi.nlm.nih.gov/gene/9971
Official Symbol
NR1H4provided by HGNC
Official Full Name
nuclear receptor subfamily 1 group H member 4provided by HGNC
Primary source
HGNC:HGNC:7967
See related
Ensembl:ENSG00000012504; HPRD:04827; MIM:603826; Vega:OTTHUMG00000170359
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BAR; FXR; HRR1; HRR-1; RIP14
Summary
This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]
Orthologs Hiiri

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?


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